Taking the teaching of basic courses of architectural design in Guizhou Minzu University as an example, this study gives a detailed review on the systematic construction of creative thinking system, such as the construction content, teaching mode, quality control, learning driving force and environmental construction. This study further proves the importance and feasibility of the construction of creative thinking system in ATN.CDIO (Art Technology Nationality Conceive Design Implement Operate) engineering education mode. In addition, this study analyzes and summarizes the teaching results obtained, proposes bottlenecks in future development, and improves the breadth and depth of ATN.CDIO teaching mode.