With the continuous expansion of graduate enrollment, local colleges and universities bear the majority of the responsibility for graduate education. Due to geographical and resource limitations, local universities in the western region are facing problems such as weak guidance and teaching staff, homogeneous competition incentives in disciplines, and insufficient innovation ability of students. How to ensure the quality of graduate education is a concern of all sectors of society. In response to the above issues, this article takes the School of Intelligent Technology and Engineering at Chongqing University of Science and Technology as an example to explore the connotation, characteristics, and practical paths of the professional master's supervisor team cooperation system. By establishing a stable mentor cooperation model with small teams and large peripherals, the problem of insufficient teaching staff for guiding teachers can be addressed; On this basis, construct a "3+2+1" learning time unit and diverse collaborative measures to ensure the cultivation of students' engineering innovation ability; Then, establish a 5-dimensional open academic discussion atmosphere, maintain the innovation activity of teachers and students, promote deep cross integration within the school, between schools, and between schools and enterprises, and overcome the problem of homogeneous competition in disciplines. The collaborative training model of professional master's supervisors can provide reference solutions for high-quality training of professional master's students in other universities in the western region.