Aimed at the cultivating goal of civil engineering majors, this paper explores the ideological and political elements contained in the construction of large-scale civil, hydraulic and transportation engineering projects, such as innovative ideas, craftsmanship spirit and professional ethics, and develops a four-stage curriculum-based ideological and political construction path for the professional practice teaching of civil engineering majors, i.e. "entry - consolidation - improvement - sublimation". The strategy of combining "inviting in" and "going out" is developed to innovate the curriculum-based ideological and political teaching mode by integrating the role of university and enterprise. The enterprise technical experts or engineers are invited into university class as supervisors to guide the professional practice teaching, and the students are sent to the construction site of the large-scale projects. The honors belonging to China's engineering construction like "Infrastructure Powerhouse", "China Speed" and other major engineering construction achievements, as well as technological innovations are taken as the carriers to practice and put forward the curriculum-based ideological and political teaching methods for professional practice teaching of civil engineering majors, such as "getting straight to the point", "leading by role models", "scenario experience" and "implicit penetration".