This article aims to explore how to promote the distinctive development and innovative transformation of construction management major in application-oriented universities under multiple contexts. Firstly, the positioning and talent cultivation requirements for the development of construction management major are analyzed; Secondly, the focus is on exploring the possible expansion directions and deepening areas of the current development of construction management major in the "broad" and "deep" directions; Then, methods are proposed to promote professional development through the construction of micro majors and the integration of industry and education; Finally, from the aspects of avoiding arrogance and stubbornness, improving teaching abilities, overall layout, and gradually promoting implementation, precautions are be put forward when transforming and developing professional and distinctive innovation.