Construction project investment and financing is a professional course of urban management, project management and engineering cost majors in colleges and universities with strong practicality and wide application. The course of construction project investment and financing has some pain-point problems such as lack of multi-discipline integration, lack of frontier knowledge, lack of innovation, lack of practical cognition, lack of integration of theory and practice, lack of deep understanding of high-quality development strategy, and need to deepen ideological and political concepts. Aiming at the pain-point problems, the course objectives, course content, teaching mode and evaluation system were innovatively designed. Based on student-centered, course objectives were constructed from the dimensions of knowledge, ability and value. The "case database, document database and project database" were constructed for the reconstruction and optimization of course content. The "seminar, hybrid, bilingual and scene" teaching styles were introduced to realize the "three libraries and four modes" teaching mode innovation. A multi-dimensional, diversified and knowledge application-oriented curriculum evaluation system was explored. The innovative design of the course promotes the improvement of students" learning effect, and the promotion of "three libraries and four modes" teaching mode shows demonstration and radiation effects.