The teaching point of professional English course is how to improve the English application ability and the comprehensive quality of engineering specialty. According to the teaching situation and the existing problems, the paper reformed course content, teaching methods and examination mode based on the actual situation. A student-centered and interactive self-learning teaching method was presented. The teaching practice showed that the positive effect was achieved and teaching quality was improved significantly. Based on the suggestions from the students who have taken part in the reform, it established the subsequent improvement of teaching reform.