Teaching reform of programmable logic device based on CDIO engineering education model and integration of scientific research and teaching is proposed. Teaching reform model, teaching reform scheme, reform and innovation of education idea are introduced. The service engineer is identified engineering talent training target of local teaching undergraduate colleges. CDIO education mode is act as a guide. Under the support of scientific research teaching, teaching is continually developed and improved; making sure the integration of scientific research and teaching can be realized. Realizing engineering talent cultivation target are the purposes of teaching reform which can improve students’ professional knowledge, train students’ abilities, make students learn good characters and enhance students’ qualities.