To increase the teaching effect of seismic design of building structures, a new media, microblog, was combined with conventional teaching method to explore innovative teaching ideas. The advantages of microblog in teaching were analyzed first and then the teaching practice using microblog in the course of seismic design of building structures was illustrated. Finally, the existing problems in current teaching using microblog were analyzed. The practice shows that using microblog can increase the teaching effect and efficiency, which provides a reference for the optimization of teaching mode and methods.