Campus architecture, which is the carrier of campus culture and university features, is important for talent training. Traditional Chinese Medicine (TCM) roots in traditional Chinese culture and the spirit of humanities is the soul of TCM talents. We take Yunnan University of TCM as an example and state that campus architecture plays an important role in training the spirit of TCM humanities. The architecture of Yunnan University of TCM takes “Qin brick & Han tile, sky circle & earth square, Han & Tang style” as main design elements, and carries forward that the spirit of humanities and the educational theory of TCM, which makes it good works of new campus construction in China.