The collaborative innovation is another major strategic deployment after the Project 211 and Project 985 by the government. It brings great opportunities and challenges for the education reform in colleges and universities in China. This paper compared the differences existed among the first planed and led units as well as the local colleges and universities in 2011 in the aspect of scientific research platforms from the talent advantages, the academic disciplines, the bases and so on. It shows the difficult in starting the collaborative innovation in the local colleges and universities and puts forward the exploratory opinions.