Under the new background of the Education and Training Program of Excellence Engineers (E&TPEE), the education and training for college engineering talents have higher requirements than before. The practice teaching of the environmental engineering major in Henan Polytechnic University (HPU) has been carried out for many years. Many deficiencies and experience have been accumulated from aspects of students, teachers, colleges and enterprises. According to the talent training objectives of E&TPEE, the reform on the practice teaching of environmental engineering major was carried out, expanding the production practice to four steps: enterprise visiting, simulation experiment, post exercising and environmental monitoring, and focusing on the cultivation of engineering practice ability and innovation ability to achieve a win-win situation and development of colleges, students and enterprises.