The arrival of the era of big data brings challenges to traditional intellectual property education in universities. By combing the connotation of big data and the necessity and importance of intellectual property education in universities, the relationship between big data and intellectual property education of universities was interpreted. On this basis, suggestions for specific application of big data in universities' intellectual property education were made from three aspects: to enhance teachers and students' literacy of big data, to build the network teaching platform, and to creat multivariate evaluation system, to provide reference for a better application of big data in the field of universities' intellectual property education.