The civil engineering specialty faced enormous challenges to the application-oriented transformation in various universities. Based on this, the paper analyzed and summarized the existing problems in the present talents cultivation mode in Dalian Ocean University, and put forward a number of related solutions, such as guided by practicing qualification registered engineer system, locating the talents cultivation target and ability requirements, optimizing the structure of curriculum knowledge and content, utilizing the internet innovation teaching methods, strengthening practice teaching management, perfecting the talent assessment and evaluation mechanism, and intensifying the construction of double type teaching staff. A full range of engineering education reform of the civil engineering was executed to realize moderate cohesion between the knowledge and the latest practice registration system, and further building regional engineering applied talents training system with distinctive features. These measures can improve students' engineering application ability and employability, and also provide the idea and reference for the construction of civil engineering in similar universities across the country.