Construction project investment and financing is a professional course of urban management, project management and engineering cost majors in colleges and universities with strong practicality and wide application. The course has some pain-point problems such as lack of multi-discipline integration, lack of frontier knowledge, lack of innovation, lack of practical cognition, lack of integration of theory and practice, lack of deep understanding of high-quality development strategy, and need to deepen ideological and political concepts. Aiming at the problems, the course objectives, course content, teaching mode and evaluation system are innovatively designed. The course objectives are constructed from the dimensions of knowledge, ability and value. The case database, document database and project database are constructed for the reconstruction and optimization of course content. The seminar, hybrid, bilingual and scene teaching styles are introduced to realize the three libraries and four modes teaching mode innovation. A multi-dimensional, diversified and knowledge application-oriented curriculum evaluation system is explored. The innovative design promotes students’ learning effect, and the promotion of three libraries and four modes teaching mode shows demonstration and radiation effects.